CJC1295 - NO DAC

CJC-1295 (No DAC) is a synthetic growth hormone–releasing hormone (GHRH) analogue designed for research into pulsatile growth hormone (GH) secretion. Unlike the DAC-modified version, No DAC has a shorter half-life, making it ideal for studies focused on natural GH pulse dynamics rather than prolonged elevation.

This peptide is widely investigated in endocrine, metabolic, recovery, and body composition research, particularly where controlled GH release is preferred.

Key Features

💉 Research-grade peptide formulation
⏱️ Short-acting (No DAC) for physiologic GH pulsatility
🧬 Mimics endogenous GHRH signalling
🧪 High-purity, laboratory-tested compound
📄 Supplied for laboratory research use only

Key Research Benefits

📈 Stimulates Endogenous Growth Hormone Release
• Activates pituitary GH secretion through GHRH receptor binding

⚙️ Supports Natural GH Pulses
• Short half-life allows investigation of physiologic GH rhythm

💪 Recovery & Tissue Repair Research
• Relevant to studies on muscle recovery, connective tissue, and regeneration pathways

🔥 Metabolic & Fat Utilisation Research
• GH signalling plays a role in lipolysis and metabolic efficiency

🧠 Sleep & Circadian Rhythm Studies
• GH release is closely linked to sleep-related endocrine patterns

Mechanism Overview

CJC-1295 (No DAC) binds to GHRH receptors in the pituitary, stimulating:

• Growth hormone secretion

• IGF-1 signalling (indirectly)

• Protein synthesis and tissue repair pathways

The No DAC structure ensures rapid clearance, supporting short-duration GH signalling rather than sustained elevation.

Human-Relevant Research Applications

🔬 Endocrine and GH pulse modelling
🔬 Recovery and tissue repair research
🔬 Metabolic and fat-oxidation pathways
🔬 Sleep-related hormone regulation
🔬 Performance and longevity signalling studies