VIP

Vasoactive Intestinal Peptide (VIP) is a next‑generation peptide research formula designed to support nervous system function, balanced immunity, and respiratory health through multi‑system regulatory pathways. By influencing neuroimmune signaling, smooth muscle relaxation, and anti‑inflammatory mechanisms, VIP is studied for its role in cognitive support, immune modulation, and respiratory homeostasis.

This formulation is ideal for research models focused on neuroprotection, immune regulation, inflammation balance, pulmonary function, and systemic wellness in human‑relevant studies.

Key Features

🧪 cGMP manufactured in an FDA‑registered facility
✅ ≥98% purity confirmed by HPLC analysis
📄 Batch‑specific Certificates of Analysis (COAs) included
💉 Sterile, lyophilized vials for research use only

Human‑Relevant Research Applications

🧠 Neuroimmune & Immune Regulation
VIP functions as a neuropeptide and immune regulator by modulating cytokine signaling, downregulating pro‑inflammatory mediators, and promoting tolerogenic responses — relevant for studies on inflammation control and immune homeostasis.
🔗 https://pubmed.ncbi.nlm.nih.gov/22139413/

🫁 Respiratory & Bronchodilatory Function
VIP has potent bronchodilatory and vasodilatory effects and is being explored for its role in respiratory therapeutics, including modulation of airway smooth muscle and pulmonary inflammation.
🔗 https://pubmed.ncbi.nlm.nih.gov/23935337/

⚖️ Smooth Muscle Relaxation & Vascular Effects
VIP’s homeostatic effects on smooth muscle include inhibition of NF‑κB signaling during inflammatory insults and reversal of inflammatory dysfunction in smooth muscle tissues, supporting research into vascular and respiratory regulation.
🔗 https://pubmed.ncbi.nlm.nih.gov/19661154/

🛡️ Anti‑Inflammatory & Autoimmunity Research
VIP is a potent anti‑inflammatory factor that controls innate and adaptive immune responses, making it relevant for studies on immune dysregulation, autoimmunity, and chronic inflammation.
🔗 https://pubmed.ncbi.nlm.nih.gov/11862320/

Mechanism Summary

• Modulates neuroimmune signaling and cytokine expression

• Inhibits pro‑inflammatory pathways while promoting immune tolerance

• Promotes bronchodilation and smooth muscle relaxation

• Supports human‑relevant studies in respiratory, immune, and neuroprotective research

Reconstitution & Handling Guidance

1️⃣ Use sterile bacteriostatic water (0.9% benzyl alcohol)
2️⃣ Add 1–3 ml of bacteriostatic water to reconstitute the peptide (adjust as needed for your experimental concentration)
3️⃣ Gently swirl until fully dissolved (do not vortex)
4️⃣ Store reconstituted peptide at 4 °C–10 °C for 2–3 months
5️⃣ Unreconstituted peptide can be stored at 4 °C–10 °C until the expiration date