HEXARELIN

Hexarelin is a synthetic growth hormone-releasing peptide (GHRP) developed to strongly stimulate the pituitary gland to release endogenous growth hormone (GH). Known for its high potency, Hexarelin is studied for its role in muscle growth, fat metabolism, recovery, and anti-aging research.

Unlike many GH secretagogues, Hexarelin has also been investigated for direct cardiovascular effects, including improved cardiac performance and vascular support, making it a unique peptide in both performance-focused and regenerative research settings.

Key Features

🧪 cGMP manufactured in an FDA-registered facility
✅ ≥98% purity confirmed by HPLC analysis
📄 Batch-specific Certificates of Analysis (COAs) included
💉 Sterile, lyophilized vials for research use only

Human-Relevant Research Applications

🔬 Potent growth hormone release in healthy adults
This clinical study shows that Hexarelin administration significantly increases GH secretion in healthy human volunteers in a dose-dependent manner — more than growth hormone-releasing hormone (GHRH).
🔗 https://pubmed.ncbi.nlm.nih.gov/8126144/

💪 Dose-dependent GH release confirmed in humans
A placebo-controlled dose-response study in healthy male subjects demonstrated reproducible, dose-related increases in circulating growth hormone following Hexarelin.
🔗 https://pubmed.ncbi.nlm.nih.gov/7957536/

❤️ Cardiac performance improvement in patients with coronary artery disease
In people undergoing bypass surgery, acute Hexarelin administration was shown to improve cardiac performance metrics, supporting cardiovascular research interest beyond GH effects.
🔗 https://pubmed.ncbi.nlm.nih.gov/12144941/

Mechanism Summary

• Activates growth hormone secretagogue receptors (GHS-R) in the pituitary to stimulate GH release

• Engages GH/IGF-1 signaling pathways relevant to muscle growth, recovery, and fat metabolism

• Interacts with GHS-R expressed in cardiac tissue, contributing to direct cardiovascular effects

• Supports research into anabolic signaling, metabolic regulation, and cardioprotective pathways

Reconstitution & Handling Guidance

1️⃣ Use sterile bacteriostatic water (0.9% benzyl alcohol)
2️⃣ Add 3 ml of bacteriostatic water to reconstitute the peptide
3️⃣ Gently swirl until fully dissolved (do not vortex)
4️⃣ Store reconstituted peptide at 4 °C–10 °C for 2–3 months
5️⃣ Unreconstituted peptide can be stored at 4 °C–10 °C until the expiration date

Legal & Research Disclaimer

This material is supplied exclusively for laboratory research use. It is not intended for diagnostic, therapeutic, cosmetic, human, or veterinary applications. The purchaser assumes all responsibility for compliance with applicable local, state, and federal regulations governing research compounds.