Pinealon 10mg

Pinealon is a synthetic tripeptide consisting of the amino acid sequence glutamic acid, aspartic acid, and arginine. It’s also known as EDR peptide. Research suggests that Pinealon’s mechanism of action involves activating the gene expression and the synthesis of proteins associated with neuronal activity, as well as decreasing the intensity of neuronal cell death.

Key Features:

• MAPK/ERK signaling pathway: The MAPK/EKR signaling pathway is important for cell proliferation, cell differentiation, and the elimination of damaged cells, among other things.

• Proapoptotic proteins: Proapoptotic proteins help trigger apoptosis, or programmed cell death, which is critical for removing damaged or unwanted cells (cancer cells). Examples of proapoptotic proteins activated by Pinealon are caspase-3 and p53 
• Antioxidant proteins: Antioxidant proteins play a critical defensive role against free radicals and reactive oxygen species, the proliferation of which can lead to dysregulated apoptosis, which in turn is associated with pathologies such as autoimmune diseases, cancer, and neurodegeneration

Research Reference:
A peptidomimetic targeting adipose vasculature has been shown in preclinical studies to induce selective apoptosis of blood vessels supplying white adipose tissue, leading to adipose tissue atrophy and metabolic effects in research models. https://pubmed.ncbi.nlm.nih.gov/22072637/